We consider the influence that John Forrester’s work has had on thinking in, with, and from cases in multiple disciplines. Forrester’s essay ‘If p, Then What? Thinking in Cases’ was published in History of the Human Sciences in 1996 and transformed understandings of what a case was, and how case-based thinking worked in numerous human sciences (including, centrally, psychoanalysis). Forrester’s collection of essays Thinking in Cases was published posthumously, after his untimely death in 2015, and is the inspiration for the (...) special issue we introduce. This comprises new research from authors working in and across the history of science and medicine, gender and sexuality studies, philosophy of science, semiotics, film studies, literary studies and comparative literature, psychoanalytic studies, medical humanities, and sociology. This research addresses what it means to reason in cases in particular temporal, spatial, or genre-focused contexts; introduces new figures (e.g. Eugène Azam, C. S. Peirce, Michael Balint) into lineages of case-based reasoning; emphasizes the unfinished and unfinishable character of some case reading and autobiographical accounts; and shows the frequency with which certain kinds of reasoning attempted with cases fail (often in instructive ways). The special issue opens up new directions for thinking and working with cases and case-based reasoning in the humanities and human sciences. (shrink)

Ce texte vise à proposer quelques arguments pour une critique empiriste de la hiérarchie des normes, c'est-à-dire pour les besoins d'une science du droit descriptive et explicative. La hiérarchie des normes est à la fois objet d’étude scientifique, et théorie construisant cet objet. Une approche empiriste nécessite la formalisation de quelques concepts et une justification minimale de la possibilité d'une science juridique empiriste : ce seront les objets des premiers points de ce texte. Il s'agira ensuite de proposer une formulation (...) de la conception de la hiérarchie des normes à laquelle l’empirisme peut conduire, permettant de réévaluer la théorie (normativiste) de la hiérarchie des normes proposée par Kelsen comme une théorie politique, qui ne décrit pas son objet mais le construit comme contrainte. (shrink)

~Et h i c a l sensitivity is investigated in an illustrative analysis of two female television nezos viewers. Transcripts of structured, in-depth interviews were analyzed according to four critical content dimensions of ethical sensitivity reflecting interviewees' mentions of story characteristics, ethical issues, consequences, and stakeholders. Cognitive maps illustrate the reasoning processes ofthe two viewers, one with relatively high and the other with relatively low ethical sensitivity. This study provides a detailed description of a new application of a research procedure, (...) and gives detailed examples of how subdimensions of ethical sensitivity interact and relate to a person's reasoning processes. The study is a pilot demonstration of a promising methodology and a precursor to more investigations on more viewers, more types of content, and more media. (shrink)

Synthetic biologists design and engineer organisms for a better and more sustainable future. While the manifold prospects are encouraging, concerns about the uncertain risks of genome editing affect public opinion as well as local regulations. As a consequence, biosafety and associated concepts, such as the Safe-by-design framework and genetic safeguard technologies, have gained notoriety and occupy a central position in the conversation about genetically modified organisms. Yet, as regulatory interest and academic research in genetic safeguard technologies advance, the implementation in (...) industrial biotechnology, a sector that is already employing engineered microorganisms, lags behind. The main goal of this work is to explore the utilization of genetic safeguard technologies for designing biosafety in industrial biotechnology. Based on our results, we posit that biosafety is a case of a changing value, by means of further specification of how to realize biosafety. Our investigation is inspired by the Value Sensitive Design framework, to investigate scientific and technological choices in their appropriate social context. Our findings discuss stakeholder norms for biosafety, reasonings about genetic safeguards, and how these impact the practice of designing for biosafety. We show that tensions between stakeholders occur at the level of norms, and that prior stakeholder alignment is crucial for value specification to happen in practice. Finally, we elaborate in different reasonings about genetic safeguards for biosafety and conclude that, in absence of a common multi-stakeholder effort, the differences in informal biosafety norms and the disparity in biosafety thinking could end up leading to design requirements for compliance instead of for safety. (shrink)

Decompressive craniectomy is a technically straightforward procedure whereby a large section of the cranium is temporarily removed in cases where the intracranial pressure is dangerously high. While its use has been described for a number of conditions, it is increasingly used in the context of severe head injury. As the use of the procedure increases, a significant number of patients may survive a severe head injury who otherwise would have died. Unfortunately some of these patients will be left severely disabled; (...) a condition likened to the RUB, an acronym for the Risk of Unacceptable Badness. Until recently it has been difficult to predict this outcome, however an accurate prediction model has been developed and this has been applied to a large cohort of patients in Western Australia. It is possible to compare the predicted outcome with the observed outcome at 18 months within this cohort. By using predicted and observed outcome data this paper considers the ethical implications in three cases of differing severity of head injury in view of the fact that it is possible to calculate the RUB for each case. (shrink)

The rule of rescue describes the powerful human proclivity to rescue identified endangered lives, regardless of cost or risk. Deciding whether or not to perform a decompressive craniectomy as a life-saving or ‘rescue’ procedure for a young person with a severe traumatic brain injury provides a good example of the ethical tensions that occur in these situations. Unfortunately, there comes a point when the primary brain injury is so severe that if the patient survives they are likely to remain severely (...) disabled and fully dependent. The health resource implications of this outcome are significant. By using a web-based outcome prediction model this study compares the long-term outcome and designation of two groups of patients. One group had a very severe injury as adjudged by the model and the other group a less severe injury. At 18 month follow-up there were significant differences in outcome and healthcare requirements. This raises important ethical issues when considering life-saving but non-restorative surgical intervention. The discussion about realistic outcome cannot be dichotomised into simply life or death so that the outcome for the patient must enter the equation. As in other ‘rescue situations’, the utility of the procedure cannot be rationalised on a mere cost–benefit analysis. A compromise has to be reached to determine at what point either the likely outcome would be unacceptable to the person on whom the procedure is being performed or the social utility gained from the rule of rescue intervention fails to justify the utilitarian value and justice of equitable resource allocation. (shrink)

This study examines the non-linear effects of ESG performance on firm value in Chinese A-share listed firms from 2009 to 2023, addressing a gap in emerging-market ESG research that often assumes a linear, universally positive relationship. Using 29,439 firm-year observations and performance measures including Tobin's Q, ROA, and ROE, the study applies two-way fixed-effect, Lind-Mehlum U-tests, and robustness checks with alternative ESG ratings (Bloomberg and Huazheng) and by excluding extreme market shocks (the 2015 stock market crash and COVID-19). The (...) findings reveal a robust inverted U-shaped relationship, demonstrating that moderate ESG engagement enhances firm performance, whereas excessive ESG investment results in diminishing or even negative returns. Heterogeneity analyses show that this effect is strongest in non-state-owned, financially unconstrained, and high-polluting firms, while SOEs and constrained firms exhibit weaker or more linear effects. Pillar-level analysis highlights environmental and governance dimensions as primary drivers, whereas social initiatives have limited impact. The study's novelty lies in providing empirical evidence for the curvilinear ESG-performance link in an emerging market context, advancing theory by showing that ESG investments create intangible assets such as legitimacy, trust, and innovation only up to an optimal threshold, with institutional and financial contexts shaping the relationship. These insights inform policymakers and managers to calibrate ESG strategies strategically, and motivate future research across other markets, ESG ratings, and causal designs. (shrink)

This paper describes a new theory of consciousness based on previous work by C.D. Broad, H.H. Price, Andrei Linde and others. This hypothesis states that the Universe consists of three fundamental entities - space-time, matter and consciousness, each with their own degrees of freedom. The paper pays particular attention to three areas that impact on this theory: the demonstration by neuroscience and psychophysics that we do not perceive the world as it actually is but as the brain computes it most (...) probably to be; the need to delineate between phenomenal space-time and physical space-time. Recent theories in physics that suggest that the Universe has more than three spatial dimensions are relevant here; the role of consciousness in the block Universe described by Special Relativity. The integration of these topics suggests a new physical theory of the nature of consciousness. (shrink)

Dignified care is a central issue in the nursing care of older adults. Nurses are expected to treat older adults with dignity, and older adults wish to be treated in a dignified manner. Researchers have recommended investigating the concept of dignity based on specific contexts and population groups. This meta-synthesis study aims to explore the understandings of dignity from the perspective of older adults in the Nordic countries. Synthesising findings from qualitative studies on older adults’ experiences of dignity has provided (...) important insight into what can be essential for dignified care in a Nordic context. The importance of visibility and recognition for the experience of dignity is an overarching theme in all the studies. The participants’ descriptions mostly implicated an existence dominated by a lack of recognition. The older adults do not feel valued as people or for their contribution to society and strive to tone down their illnesses in an attempt to become more visible and acknowledged as people. Toning down their illnesses and masking their needs can protect their independence. At the same time, becoming less visible can leave them without a voice. The metaphorical phrase protected and exposed by a cloak of invisibility is used to express the authors’ overall interpretation of the findings. Lack of recognition and being socially invisible is a genuine threat to older adults’ dignity. (shrink)

Big data enables researchers to closely follow the behavior of large groups of individuals by using high-frequency digital traces. However, these digital traces often lack context, and it is not always clear what is measured. In contrast, data from ethnographic fieldwork follows a limited number of individuals but can provide the context often lacking from big data. Yet, there is an under-explored potential in combining ethnographic data with big data and other digital data sources. This paper presents ways that quantitative (...) research designs can combine big data and ethnographic data and account for the synergies that such combinations can provide. We highlight the differences and similarities between ethnographic data and big data, focusing on the three dimensions: individuals, depth of information, and time. We outline how ethnographic data can validate big data by providing a “ground truth” and complement it by giving a “thick description.” Further, we lay out ways that analysis carried out using big data could benefit from collaboration with ethnographers, and we discuss the potential within the fields of machine learning and causal inference. (shrink)

How do people survive under extreme conditions? Will selfish, non-cooperating free-rider types – the solo players – have the best chances of surviving? Or would cooperating, hard-working types – the team players – have higher chances? All morale put aside, it is interesting to know whether non-cooperation or cooperation pays off in a game characterized by scarcity and hard competition for survival. A study of people in such a Hobbesian state of nature can also teach us important lessons about social (...) dynamics in contemporary, prosperous societies. An interesting case of ‘The survival game’ can be found in Solzhenitsyn’s (1963 [1962]) self-biographical book, One Day in the Life of Ivan Denisovich, depicting life in a Soviet Gulag prison camp in Siberia January 1951. We use Solzhenitsyn’s work as evidence of the interplay between five player types among prisoners: Cooperative blind-riders (BRs), hard-riders (HRs) and tough-riders (TRs), i.e. the so-called ‘toilers’; non-cooperative easy-riders (ERs), looked upon by the toilers as ‘bastards’, ‘screws’ and ‘errand boys’; and finally Low-riders (LRs), comprising ‘goners’ and ‘jackals’. The main research question addresses the successfulness of the survival strategies of the five player types. Apart from a Multiple Player Approach (MPA) that may be seen as a further development of second-generation theory of collective action (Ostrom & Ahn, 2009), we apply Goffman’s (1959) dramaturgical theory on our case. Hence, we argue that impression management at two different ‘stages’ – the Brigade stage and the Camp stage – is crucial for survival for hard-riding as well as for easy-riding players, in particular strategic masking. Seeking to unite Goffman and game-theoretic MPA, our overall purpose is to make a theoretical contribution to “game-related sociology” (Swedberg, 2001). (shrink)

This work attempts to deconstruct Jair Bolsonaro’s hostile policy vis-à-vis the Brazilian media during his presidency by applying Zygmunt Bauman’s description of “liquid modernity” and its aversion to “strangeness” as the sociological-philosophical apparatus combined with the presidential-press relationship and the enemy construction dynamics of the communication research. The explorative qualitative empirical analysis of three-dimensional anti-media categories traditionally associated with right-wing populists—the discrediting and blaming of the press and detaching it from the people—throughout the “honeymoon” period of Bolsonaro’s presidency confirmed the (...) decoupling of the traditional presidential-press and media-public relationships. Besides validating the primacy of the logic of consumption over morality, it further corroborated the fiercely adversarial populist policy designed for strangeness rhetoric construction of the media as distrusted “outsider” and “enemy.”. (shrink)

In Michel Henry’s studies, the absence of Pascal in the phenomenology of life has been mentioned. Nevertheless, it is noteworthy that the author of Pensées is mentioned both in Henry’s main work, The Essence of Manifestation, and in the Christic trilogy, which showcases the radical limits of his own phenomenology. In this article, we aim to analyze the few explicit references that Henry makes to Pascal to demonstrate how the author of Pensées serves as one of the allies of the (...) radical phenomenologist in the corroboration of two of his fundamental intuitions. (1) First, that the self-affection of the “heart” precedes any hetero-affection where the objectifying reason is put into action ; (2) second, that the human person is realized in an inner experience where the “heart” lives the link with God, who gives our life in fullness. To believe in God is to have this experience. Consequently, Pascalian apologetics is translated in Henry’s phenomenological description of the immanent link to God understood as absolute life. In doing so, Henry distinguishes Pascal from Heidegger by highlighting that within our acosmic heart, what emerges is not a being-towards-death, but rather an ipseity-from-absolute-Life. (shrink)

For Aristotle, happiness (eudaimonia) would constitute the end of all human action, whether contemplative, practical, or moral. In such a teleological approach, human nature is realized to the extent that it attains the state of happiness. Moreover, this state should be subjectively apprehended by the person him or herself as a feeling of fulfillment.The experience of vulnerability stood out with the crisis caused by the Covid-19 pandemic, whose consequences extend to the most diverse areas of human societies, from economics to (...) mental health. Despite the technological and economic progress achieved, especially in the West, science has not been able to predict and prevent the emergence and spread of the virus. Thus, in a world surprised by the rapid and deadly spread of the Sars-CoV-2 virus, the feeling of insecurity has come to inhabit people’s lives. Forced to wear a mask and deal with continuous confinements in order to mitigate the spread of the virus, we feel life changing regardless of the wealth produced and knowledge achieved.We want to show how this experience of vulnerability may constitute an opportunity. In order to do so, we will expose an ontology of the We, a metaphysics of love, based on four authors—Simon L. Frank, Ferdinand Ulrich, Elena Lasida, and Minouche Shafik—who tend to be neglected by the current philosophical landscape. In doing so, instead of deconstructing the paradigm of modern scientism, which after the crisis fell into disrepute, we will rather show the possibility of establishing a dialogical approach that sees dependence and vulnerability not as something that must be overcome: this is precisely the human condition from which a person can realize his or her life in this world, reaching its fullness. This is possible in the horizon of the communion of love between different people and not so much from a reason that each subject holds and that allows him to know, predict, and dominate the world. (shrink)

This article analyzes Teilhard’s references to Marxism, highlighting his dialogue with the influential Marxist thought of the 20th century. Despite not deeply engaging with Marx’s works, Teilhard acknowledges the significance of Marxist ideas within the cultural context of the last century. Positioned within the framework of grand narratives, Teilhard’s Christian perspective offers an alternative to Marxism, emphasizing a comprehensive understanding of reality that integrates spiritual and material dimensions. By exploring Teilhard’s interactions with Marxism, this study sheds light on the complex (...) intellectual landscape of the era, where competing ideologies shaped debates about the meaning of human existence and history. (shrink)

Abstract:This essay examines the ways that the 2008 Constitution resignified Ecuador as a “plurinational” state, one that respects and affirms the sovereignty of the diverse Indigenous and Afro-descendent groups within it, as well as the ways that it redefined the family, shifting from a singular notion of family to one based on a notion of la familia diversa, the family in its diverse forms. We'll suggest that these linked redefinitions share a similar logic of multiplicity and open-endedness that work to (...) challenge monolithic and hegemonic social and political forms that had been imposed on Ecuador in a colonial context and then preserved in the postcolonial period. In doing so, we pay particularly close attention to the development of these concepts in contemporary Ecuadorian politics, as well as to ways in which their implementation has been limited, compromised, and forestalled. We argue that, far from being a change only on paper, the opening up of the definitions of the nation and the family in the Ecuadorian Constitution are important aspects of linguistic and institutional resistance to the coloniality of power in Ecuador. We explore ways that Ecuadorian activists maneuver the contradictions and challenges of engaging with the state in doing this work. (shrink)

Through an analysis of 100 asylum decisions and 10 interviews with 20 asylum officers at the Swedish Migration Agency this article reveals two intricate processes through which children’s rights are displaced in the Swedish asylum process; by overlooking children’s individual claims for asylum through a circle of neglect, and negating children’s best interests. The article demonstrates how the balancing act between migration control on one hand and children’s rights on the other hand plays out in the asylum process, which results (...) in a double displacement; the children are not adult enough to be addressed as asylum seekers and not children enough to deserve qualification as bearer of children’s rights. An in-depth analysis of everyday practices at institutions applying children’s rights is essential both to understand the reproduction of discrepancies between rights on paper and rights in practice, and to explore the potential of rights to disrupt oppressive vehicles of power. (shrink)

Political candidates often believe they must focus their campaign efforts on a small number of swing voters open for ideological change. Based on the wisdom of opinion polls, this might seem like a good idea. But do most voters really hold their political attitudes so firmly that they are unreceptive to persuasion? We tested this premise during the most recent general election in Sweden, in which a left- and a right-wing coalition were locked in a close race. We asked our (...) participants to state their voter intention, and presented them with a political survey of wedge issues between the two coalitions. Using a sleight-of-hand we then altered their replies to place them in the opposite political camp, and invited them to reason about their attitudes on the manipulated issues. Finally, we summarized their survey score, and asked for their voter intention again. The results showed that no more than 22% of the manipulated replies were detected, and that a full 92% of the participants accepted and endorsed our altered political survey score. Furthermore, the final voter intention question indicated that as many as 48% (69.2%) were willing to consider a left-right coalition shift. This can be contrasted with the established polls tracking the Swedish election, which registered maximally 10% voters open for a swing. Our results indicate that political attitudes and partisan divisions can be far more flexible than what is assumed by the polls, and that people can reason about the factual issues of the campaign with considerable openness to change. (shrink)

The legacy of Nisbett and Wilson’s classic article, Telling More Than We Can Know: Verbal Reports on Mental Processes , is mixed. It is perhaps the most cited article in the recent history of consciousness studies, yet no empirical research program currently exists that continues the work presented in the article. To remedy this, we have introduced an experimental paradigm we call choice blindness [Johansson, P., Hall, L., Sikström, S., & Olsson, A. . Failure to detect mismatches between intention and (...) outcome in a simple decision task. Science, 310, 116–119.]. In the choice blindness paradigm participants fail to notice mismatches between their intended choice and the outcome they are presented with, while nevertheless offering introspectively derived reasons for why they chose the way they did. In this article, we use word-frequency and latent semantic analysis to investigate a corpus of introspective reports collected within the choice blindness paradigm. We contrast the introspective reasons given in non-manipulated vs. manipulated trials, but find very few differences between these two groups of reports. (shrink)

Dans les sociétés démocratiques, le droit est le texte où s'écrivent nos croyances fondatrices : croyances en une signification de l'être humain, croyances dans la force des lois et l'empire de la justice, croyances dans les valeurs sociales de l'Interdit. Le droit impose donc un sens commun qui permet aux individus de se lier entre eux et de vivre ensemble, il fonctionne aussi comme une vérité du moment. Il se nourrit et accompagne les transformations sociales et culturelles qui touchent non (...) seulement les sociétés nationales, mais également l'espace mondialisé. Le droit enregistre, selon ses propres temporalités, les changements de valeurs, l'émergence de nouvelles inquiétudes, l'évolution des techniques et des connaissances. Depuis quelques années, nous assistons à une "demande" accrue de droit et de régulation juridique. Nous chercherons tout d'abord à repérer et identifier les nouveaux territoires du droit en montrant comment la norme juridique contribue en permanence à réinventer le réel, à fabriquer inlassablement la condition humaine, à se présenter sans cesse comme l'instituteur du social. Ce mouvement de juridicisation du social et du politique se traduit non seulement par une prolifération et une diversification de la règle de droit, mais également par un processus parallèle de judiciarisation qui voit un certain nombre de problèmes être traités par l'institution judiciaire (politiques de santé, de sécurité, phénomènes de criminalité internationale, etc.). Entrons-nous dans un nouvel âge du droit? Ces nouvelles interactions entre la société et le droit inaugurent-elles l'ère d'une future démocratie juridique? C'est à ces questions que cet ouvrage essaie de répondre grâce à des contributions de F. Bellivier, J. Commaille, M. Delmas-Marty, M. Hastings, I. De Lamberterie, S. Leverd, A. Lourdelle, E. Millard, M. Quillé, D. Salas, J-F. Thony. (shrink)

In all fields of clinical medicine, there is an increasing awareness that outcome must be assessed in terms of quality of life and cost effectiveness, rather than merely length of survival. This is especially the case when considering decompressive craniectomy for severe traumatic brain injury. The procedure itself is technically straightforward and involves temporarily removing a large section of the skull vault in order to provide extra space into which the injured brain can expand. A number of studies have demonstrated (...) many patients going on to make a good long-term functional recovery, however, this is not always the case and a significant number survive but are left with severe neurocognitive impairment. Unfortunately, many of these patients are young adults who were previously fit and well and are, therefore, likely to spend many years in a condition that they may feel to be unacceptable, and this raises a number of ethical issues regarding consent and resource allocation. In an attempt to address these issues, we have used the analytical framework proposed by Jonsen, that requires systematic consideration of medical indications, patient preferences, quality of life and contextual features. (shrink)

Background: ICU patients’ family members are in a new, uncertain, and vulnerable situation due to the patient’s critical illness and complete dependence on the ICU nurses and physicians. Family members’ feeling of being cared for is closely linked to clinicians’ attitudes and behavior. Aim: To explore ICU nurses’ and physicians’ bedside interaction with critically ill ICU patients´ families and discuss this in light of the ethics of care. Research design: A qualitative study using participant observation, focus groups, and thematic narrative (...) analysis. Participants and research context: Data were gathered from July 2017 to August 2019, in four ICUs in Norway through 270 h of fieldwork and seven focus groups with ICU nurses and physicians. Ethical considerations: The Regional Committee for Medical and Health Research Ethics and the Norwegian Centre for Research Data approved the study. Findings: Quality of ICU family care depends on nurses’ and physicians’ attitudes, behavior, and personality traits. Three main themes were identified: being attentive, an active approach, and degree of tolerance. Discussion: The findings are discussed in light of the ethics of care and empirical research from the intensive care environment. Conclusions: This study shows that attentive, active, and tolerant clinicians represent a culture of ethical care that gives families greater freedom of action and active participation in patient care. Clinicians must not bear sole responsibility for this culture; it must have a firm basis in the hospital and ICU and be established through training, interprofessional reflection, and support of clinicians. (shrink)

Intentional weight loss can increase health risk in the long‐term, despite short‐term benefits, because human adipose tissue is widely contaminated with various lipophilic environmental contaminants, especially persistent organic pollutants (POPs). Recently, chronic exposure to low POPs has emerged as a new risk factor for common metabolic diseases and cardiovascular diseases. The amount of POPs released from adipocytes to the circulation increases during weight loss, thereby increasing POPs exposure of other critical organs. Possible harmful effects due to release of POPs during (...) weight loss are opposite to those usually expected from losing weight. It is speculated that this tradeoff can explain recent puzzling findings on intensive weight loss. The presence of POPs in adipose tissue adds a challenge to weight management and an optimal strategy of weight management needs to consider both fat mass and dynamics of POPs. (shrink)

Naloxone hydrochloride, in doses of.5 to 10 mg/kg intraperitoneally, reduced water consumption by rats fluid deprived for 24 h. Administered intracerebroventricularly, 100 micrograms of naloxone produced similar effects while doses of 50 micrograms or less had no effect. Naloxone (10 mg/kg) also reduced consumption of a palatable solution (10% sucrose, weight/volume) by nondeprived rats. Morphine sulfate (.5 to 2 mg/kg) failed to increase consumption.

Every year medical researchers make contact with a large number of cancer survivors with the aim of evaluating cancer treatment. For this reason we decided to investigate how Swedish cancer survivors perceived their participation in research studies focusing on the long-term consequences of being a survivor of gynaecological or urinary bladder cancer. Data were collected by means of two study-specific postal questionnaires, both consisting of questions covering physical symptoms, well-being and the experience of being a cancer survivor. Both questionnaires also (...) included questions evaluating the participants’ experience of being research subjects. The questionnaires were developed in close co-operation with cancer survivors. The study population consisted of 1068 cancer survivors. Of these, 95% (n=1003) reported that they thought the study was valuable and 54% (n=559) that they had been positively affected by participating. Four per cent (n=39) expressed that they had been negatively affected by their participation in the study. The vast majority of the cancer survivors thought that participating in their particular study was valuable. (shrink)